Pharmacology Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacology, including details on pharmacogenomics, drug development, new medications.

Drug development and the FDA's Critical Path Initiative.

Woosley RL, Cossman J

The Critical Path Institute, Tucson, Arizona, USA. Rwoosley@C-Path.org

Advances in biomedical research over recent decades have substantially raised expectations that the pharmaceutical industry will generate increasing numbers of safe and effective therapies. However, there are warning signs of serious limitations in the industry's ability to effectively translate biomedical research into marketed new therapies. Clinical pharmacologists should be aware of these signals and their potential impact. Here, we discuss a strategy, where clinical pharmacology can play an important role to improve the process of drug development.

Published 22 December 2006 in Clin Pharmacol Ther, 81(1): 129-33.
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