Pharmacology Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacology, including details on pharmacogenomics, drug development, new medications.

Volume 3 (2007), Issue 12 (December)

1. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
   J Mol Biol, 375(1): 217-28. [Abstract] [Full-text]
2. Comparison of molecularly imprinted solid-phase extraction (MISPE) with classical solid-phase extraction (SPE) for the detection of benzodiazepines in post-mortem hair samples.
   Forensic Sci Int, 174(1): 40-6. [Abstract] [Full-text]
3. Anti-TNF antibodies: lessons from the past, roadmap for the future.
   Handb Exp Pharmacol. [Abstract] [Full-text]
4. Human monoclonal antibodies from transgenic mice.
   Handb Exp Pharmacol. [Abstract] [Full-text]
5. Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity.
   J Am Chem Soc, 129(50): 15480-90. [Abstract] [Full-text]
6. Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
   Nat Rev Microbiol, 6(1): 41-52. [Abstract] [Full-text]
7. Integrating high-content screening and ligand-target prediction to identify mechanism of action.
   Nat Chem Biol, 4(1): 59-68. [Abstract] [Full-text]
8. The discovery of salicylate ototoxicity.
   Audiol Neurootol, 13(1): 34-6. [Abstract] [Full-text]
9. Does length-based resuscitation tape accurately place pediatric patients into appropriate color-coded zones?
   Pediatr Emerg Care, 23(12): 856-61. [Abstract] [Full-text]
10. What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice?
    J Intern Med, 263(1): 16-27. [Abstract] [Full-text]
11. Quantitative online detection of low-concentrated drugs via a SERS microfluidic system.
    Chemphyschem, 8(18): 2665-70. [Abstract] [Full-text]
12. Therapeutic applications of aptamers.
    Expert Opin Investig Drugs, 17(1): 43-60. [Abstract] [Full-text]
13. Novel therapeutic strategies in development for prostate cancer.
    Expert Opin Investig Drugs, 17(1): 13-22. [Abstract] [Full-text]
14. New technologies around biomarkers and their interplay with drug development.
    Anal Bioanal Chem, 390(1): 141-54. [Abstract] [Full-text]
15. Toward full-sequence de novo protein design with flexible templates for human beta-defensin-2.
    Biophys J, 94(2): 584-99. [Abstract] [Full-text]
16. A potent cytotoxic photoactivated platinum complex.
    Proc Natl Acad Sci U S A, 104(52): 20743-8. [Abstract] [Full-text]
17. Tamoxifen pharmacogenomics: the role of CYP2D6 as a predictor of drug response.
    Clin Pharmacol Ther, 83(1): 160-6. [Abstract] [Full-text]

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