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Synthesis of soluble multivalent glycoconjugates that target the Hc region of botulinum neurotoxin A.

Kale RR, Clancy CM, Vermillion RM, Johnson EA, Iyer SS

301 Clifton Court, Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.

The design, synthesis, and initial inhibitory studies of di- and tetravalent glycoconjugates that target the heavy chain of botulinum neurotoxin A are reported.

Published 6 April 2007 in Bioorg Med Chem Lett, 17(9): 2459-64.
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