Pharmacology Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacology, including details on pharmacogenomics, drug development, new medications.

Volume 4 (2008), Issue 3 (March)

1. Cardiac sodium channels and inherited electrophysiologic disorders: a pharmacogenetic overview.
   Expert Opin Pharmacother, 9(4): 537-49. [Abstract] [Full-text]
2. Exploring the binding pocket for pyridopyrimidine ligands at the CCK1 receptor by molecular docking.
   J Mol Model, 14(4): 303-14. [Abstract] [Full-text]
3. New taxanes in development.
   Expert Opin Investig Drugs, 17(3): 335-47. [Abstract] [Full-text]
4. Discontinued drugs in 2006: oncology drugs.
   Expert Opin Investig Drugs, 17(3): 269-83. [Abstract] [Full-text]
5. Use of virtual screening, flexible docking, and molecular interaction fields to design novel HMG-CoA reductase inhibitors for the treatment of hypercholesterolemia.
   J Phys Chem A, 112(10): 2007-11. [Abstract] [Full-text]
6. Novel molecular targets for antimalarial drug development.
   Chem Biol Drug Des, 71(4): 287-97. [Abstract] [Full-text]
7. Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation.
   Toxicol Sci, 102(2): 444-54. [Abstract] [Full-text]
8. Toxicogenomic analysis of gender, chemical, and dose effects in livers of TCDD- or aroclor 1254-exposed rats using a multifactor linear model.
   Toxicol Sci, 102(2): 291-309. [Abstract] [Full-text]
9. Retention of drug administration skills after intensive teaching.
   Anaesthesia, 63(4): 379-84. [Abstract] [Full-text]
10. Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine.
    Hum Mutat, 29(4): 461-7. [Abstract] [Full-text]
11. PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single-drug pharmacogenetics.
    Hum Mutat, 29(4): 456-60. [Abstract] [Full-text]
12. Human genome variation and pharmacogenetics.
    Hum Mutat, 29(4): 453-5. [Abstract] [Full-text]
13. Making medicines in the early modern household.
    Bull Hist Med, 82(1): 145-68. [Abstract] [Full-text]
14. Duchess, heal thyself: Elisabeth of Rochlitz and the patient's perspective in early modern Germany.
    Bull Hist Med, 82(1): 109-44. [Abstract] [Full-text]
15. Development of an aryl hydrocarbon receptor antagonist using the proteolysis-targeting chimeric molecules approach: a potential tool for chemoprevention.
    Mol Pharmacol, 73(4): 1064-71. [Abstract] [Full-text]
16. Exploiting complexity and the robustness of network architecture for drug discovery.
    J Pharmacol Exp Ther, 325(1): 1-9. [Abstract] [Full-text]
17. Design of mutant beta2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells.
    J Pharmacol Exp Ther, 325(1): 37-46. [Abstract] [Full-text]
18. Assessing abuse liability during drug development: changing standards and expectations.
    Clin Pharmacol Ther, 83(4): 622-6. [Abstract] [Full-text]
19. The yeast two-hybrid system and its role in drug discovery.
    Expert Opin Ther Targets, 12(4): 505-15. [Abstract] [Full-text]
20. New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B.
    Expert Opin Ther Targets, 12(4): 391-413. [Abstract] [Full-text]
21. Identifying targets for drug discovery using bioinformatics.
    Expert Opin Ther Targets, 12(4): 383-9. [Abstract] [Full-text]
22. Pharmacogenetic studies in depression: a proposal for methodologic guidelines.
    Pharmacogenomics J, 8(2): 90-100. [Abstract] [Full-text]
23. Ancillary risk information and pharmacogenetic tests: social and policy implications.
    Pharmacogenomics J, 8(2): 85-9. [Abstract] [Full-text]
24. Protein-protein interactions as targets for small-molecule therapeutics in cancer.
    Expert Rev Mol Med, 10: e8. [Abstract] [Full-text]
25. Quantitative structure-property relationship study for estimation of quantitative calibration factors of some organic compounds in gas chromatography.
    Anal Chim Acta, 612(2): 126-35. [Abstract] [Full-text]
26. Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design.
    Protein Sci, 17(4): 601-5. [Abstract] [Full-text]
27. A self-organizing algorithm for molecular alignment and pharmacophore development.
    J Comput Chem, 29(6): 965-82. [Abstract] [Full-text]
28. Toward robust QSPR models: Synergistic utilization of robust regression and variable elimination.
    J Comput Chem, 29(6): 847-60. [Abstract] [Full-text]
29. Novel targets and new potential: developments in the treatment of inflammation in chronic kidney disease.
    Expert Opin Investig Drugs, 17(4): 451-67. [Abstract] [Full-text]

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