Pharmacology Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacology, including details on pharmacogenomics, drug development, new medications.

Volume 4 (2008), Issue 4 (April)

1. Structural diversity of G protein-coupled receptors and significance for drug discovery.
   Nat Rev Drug Discov, 7(4): 339-57. [Abstract] [Full-text]
2. Defining drug disposition determinants: a pharmacogenetic-pharmacokinetic strategy.
   Nat Rev Drug Discov, 7(4): 293-305. [Abstract] [Full-text]
3. High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology.
   Nat Rev Drug Discov, 7(4): 358-68. [Abstract] [Full-text]
4. Cell-division inhibitors: new insights for future antibiotics.
   Nat Rev Drug Discov, 7(4): 324-38. [Abstract] [Full-text]
5. Antimicrobial prescribing trends in primary care: implications for health policy in Bahrain.
   Pharmacoepidemiol Drug Saf, 17(4): 389-96. [Abstract] [Full-text]
6. Using prescription registries to define continuous drug use: how to fill gaps between prescriptions.
   Pharmacoepidemiol Drug Saf, 17(4): 384-8. [Abstract] [Full-text]
7. Development of SCAR (sequence-characterized amplified region) markers as a complementary tool for identification of ginger (Zingiber officinale Roscoe) from crude drugs and multicomponent formulations.
   Biotechnol Appl Biochem, 50: 61-9. [Abstract] [Full-text]
8. Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.
   Bioorg Med Chem Lett, 18(8): 2562-6. [Abstract] [Full-text]
9. Design and campaign synthesis of pyridine-based histone deacetylase inhibitors.
   Bioorg Med Chem Lett, 18(8): 2525-9. [Abstract] [Full-text]
10. Exploring predictive QSAR models for hepatocyte toxicity of phenols using QTMS descriptors.
    Bioorg Med Chem Lett, 18(8): 2604-9. [Abstract] [Full-text]
11. Design of high-affinity peptide conjugates with optimized fluorescence quantum yield as markers for small peptide transporter PEPT1 (SLC15A1).
    Bioorg Med Chem Lett, 18(8): 2555-7. [Abstract] [Full-text]
12. Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors.
    Bioorg Med Chem Lett, 18(8): 2691-5. [Abstract] [Full-text]
13. Linear analogues of human beta-defensin 3: concepts for design of antimicrobial peptides with reduced cytotoxicity to mammalian cells.
    Chembiochem, 9(6): 964-73. [Abstract] [Full-text]
14. Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo.
    J Med Chem, 51(8): 2457-67. [Abstract] [Full-text]
15. India takes an open source approach to drug discovery.
    Cell, 133(2): 201-3. [Abstract] [Full-text]
16. Pharmacogenetics: from bench to byte.
    Clin Pharmacol Ther, 83(5): 781-7. [Abstract] [Full-text]
17. Pharmacogenetics: potential role in the treatment of diabetes and obesity.
    Expert Opin Pharmacother, 9(7): 1109-19. [Abstract] [Full-text]
18. The ENHANCE Study: an unusual publication of trial data raises questions beyond ezetimibe.
    Expert Opin Pharmacother, 9(7): 1067-70. [Abstract] [Full-text]
19. Detection of smuggled cocaine in cargo using MDCT.
    AJR Am J Roentgenol, 190(5): 1390-5. [Abstract] [Full-text]
20. Design and synthesis of novel leucomycin analogues modified at the C-3 position. Part II: 3-O-(3-Aryl-2-propenyl)leucomycin analogues.
    Bioorg Med Chem, 16(8): 4401-18. [Abstract] [Full-text]
21. Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design.
    Bioorg Med Chem, 16(8): 4438-56. [Abstract] [Full-text]
22. Design and synthesis of nitrate esters of aromatic heterocyclic compounds as pharmacological preconditioning agents.
    Bioorg Med Chem, 16(8): 4523-31. [Abstract] [Full-text]
23. Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting.
    Science, 320(5875): 520-3. [Abstract] [Full-text]
24. Asthma genetics: personalizing medicine.
    J Asthma, 45(4): 257-64. [Abstract] [Full-text]
25. High-throughput kinase profiling as a platform for drug discovery.
    Nat Rev Drug Discov, 7(5): 391-7. [Abstract] [Full-text]

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