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IDMap: facilitating the detection of potential leads with therapeutic targets.

Ha S, Seo YJ, Kwon MS, Chang BH, Han CK, Yoon JH

BT Solutions Team, R&D Center, Equispharm Co., Ltd, Gyeonggi Bio-Center Bld. 11Fl., 864-1, Iui-dong, Yeongtong-gu, Suwon, Gyeonggi-do 443-766, Republic of Korea.

Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. AVAILABILITY: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap

Published 20 May 2008 in Bioinformatics, 24(11): 1413-5.
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