Pharmacology Research Today is a free monthly online journal that collates and summarizes the latest research about Pharmacology, including details on pharmacogenomics, drug development, new medications.

Volume 6 (2010), Issue 10 (October)

1. Development trends for human monoclonal antibody therapeutics.
   Nat Rev Drug Discov, 9(10): 767-74. [Abstract] [Full-text]
2. Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.
   J Virol, 84(21): 11235-44. [Abstract] [Full-text]
3. Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.
   J Virol, 84(21): 11235-44. [Abstract] [Full-text]
4. Providing safe medicines for children in Nigeria: The impediments and remedies.
   Ann Afr Med, 9(4): 203-12. [Abstract] [Full-text]
5. Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules.
   J Biomed Biotechnol, 2011. [Abstract] [Full-text]
6. Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules.
   J Biomed Biotechnol, 2011. [Abstract] [Full-text]
7. Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.
   Toxicol Lett, 199(2): 111-4. [Abstract] [Full-text]
8. Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.
   Toxicol Lett, 199(2): 111-4. [Abstract] [Full-text]
9. Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.
   Toxicol Lett, 199(2): 111-4. [Abstract] [Full-text]
10. Update on new antivirals under development for the treatment of double-stranded DNA virus infections.
    Clin Pharmacol Ther, 88(5): 610-9. [Abstract] [Full-text]
11. Genetic variation in IL28B: impact on drug development for chronic hepatitis C infection.
    Clin Pharmacol Ther, 88(5): 708-11. [Abstract] [Full-text]
12. Update on new antivirals under development for the treatment of double-stranded DNA virus infections.
    Clin Pharmacol Ther, 88(5): 610-9. [Abstract] [Full-text]
13. Genetic variation in IL28B: impact on drug development for chronic hepatitis C infection.
    Clin Pharmacol Ther, 88(5): 708-11. [Abstract] [Full-text]
14. Fentanyl in postmortem forensic toxicology.
    Clin Toxicol (Phila), 48(8): 771-84. [Abstract] [Full-text]
15. Genetics for the pediatric anesthesiologist: a primer on congenital malformations, pharmacogenetics, and proteomics.
    Anesth Analg, 111(5): 1264-74. [Abstract] [Full-text]
16. Genetics for the pediatric anesthesiologist: a primer on congenital malformations, pharmacogenetics, and proteomics.
    Anesth Analg, 111(5): 1264-74. [Abstract] [Full-text]
17. Absolute quantification of toxicological biomarkers by multiple reaction monitoring.
    Methods Mol Biol, 691: 417-27. [Abstract] [Full-text]
18. FETAX assay for evaluation of developmental toxicity.
    Methods Mol Biol, 691: 257-69. [Abstract] [Full-text]
19. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
    Neurology, 75(17): 1560-6. [Abstract] [Full-text]
20. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
    Neurology, 75(17): 1560-6. [Abstract] [Full-text]
21. PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds.
    Methods Mol Biol, 685: 295-320. [Abstract] [Full-text]
22. The design, annotation, and application of a kinase-targeted library.
    Methods Mol Biol, 685: 279-91. [Abstract] [Full-text]
23. LEAP into the Pfizer Global Virtual Library (PGVL) space: creation of readily synthesizable design ideas automatically.
    Methods Mol Biol, 685: 253-76. [Abstract] [Full-text]
24. Fragment-based drug design.
    Methods Mol Biol, 685: 241-52. [Abstract] [Full-text]
25. Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.
    Methods Mol Biol, 685: 191-215. [Abstract] [Full-text]
26. Structure-based library design in efficient discovery of novel inhibitors.
    Methods Mol Biol, 685: 175-90. [Abstract] [Full-text]
27. Docking methods for structure-based library design.
    Methods Mol Biol, 685: 155-74. [Abstract] [Full-text]
28. Combinatorial library design from reagent pharmacophore fingerprints.
    Methods Mol Biol, 685: 135-52. [Abstract] [Full-text]
29. Application of Free-Wilson selectivity analysis for combinatorial library design.
    Methods Mol Biol, 685: 91-109. [Abstract] [Full-text]
30. A scalable approach to combinatorial library design.
    Methods Mol Biol, 685: 71-89. [Abstract] [Full-text]
31. Molecular library design using multi-objective optimization methods.
    Methods Mol Biol, 685: 53-69. [Abstract] [Full-text]
32. Chemoinformatics and library design.
    Methods Mol Biol, 685: 27-52. [Abstract] [Full-text]
33. Historical overview of chemical library design.
    Methods Mol Biol, 685: 3-25. [Abstract] [Full-text]
34. Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.
    Nat Rev Drug Discov, 9(11): 883-97. [Abstract] [Full-text]
35. The importance of new companies for drug discovery: origins of a decade of new drugs.
    Nat Rev Drug Discov, 9(11): 867-82. [Abstract] [Full-text]
36. Accelerating the pulse of cardiovascular R&D.
    Nat Rev Drug Discov, 9(11): 823-4. [Abstract] [Full-text]
37. Developing drug prototypes: pharmacology replaces safety and tolerability?
    Nat Rev Drug Discov, 9(11): 856-65. [Abstract] [Full-text]

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